Studies on human platelet protein phosphatase(s).
نویسندگان
چکیده
منابع مشابه
Studies on human platelet proteins.
D URING the last ten years evidence has been presented from different laboratories that fibrinogen may not be essential for thrombin-mediated platelet aggregation.14 Although the presence, in platelets, of a thrombinsensitive protein other than fibrinogen has been reported from this laboratory and also by other workers,5 #{176} there is no report of its isolation, structure, physicochemical pro...
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Gangliosides, glycosphingolipids which contain sialic acid, were studied in human platelets. They represented 0.5% of the platelet lipids and accounted for 6% of the total neuraminic acid content of platelets. Three major ganglioside fractions were identified and characterized. Ganglioside I was hematoside (G(6)) and comprised 92% of the platelet gangliosides. It contained glucose, galactose, a...
متن کاملStudies on human platelet protease activity.
SOLUBILIZED PROTEIN DERIVED FROM HUMAN PLATELETS WAS FRACTIONATED BY DEAE CELLULOSE COLUMN CHROMATOGRAPHY AND ANALYZED FOR PROTEASE ACTIVITY USING THREE SUBSTRATES: denatured bovine hemoglobin, alpha casein, and purified plasminogen-free human fibrinogen. A protein fraction was found with proteolytic activity which was heat labile and not attributable to plasmin. The activity was not potentiate...
متن کاملProtein Tyrosine Phosphatases in the Human Genome
Tyrosine phosphorylation is catalyzed by protein tyrosine kinases, which are represented by 90 genes in the human genome. Here, we present the set of 107 genes in the human genome that encode members of the four protein tyrosine phosphatase (PTP) families. The four families of PTPases, their substrates, structure, function, regulation, and the role of these enzymes in human disease will be disc...
متن کاملStudies on Platelet Proteins
T HE IMPORTANCE of blood platelets in hemostasis is now well established.’ Many of the physiologic properties of platelets suggest the presence of a contractile protein and Bettex-Galland and L#{252}scher ( 1961 ) succeeded in isolating such a contractile protein, thrombosthenin, and studied some of its properties.24 Grette ( 1962 ) confirmed the presence of this protein in pig platelets.5 Sinc...
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ژورنال
عنوان ژورنال: Blood & Vessel
سال: 1988
ISSN: 0386-9717,1884-2372
DOI: 10.2491/jjsth1970.19.273